Juventus are without Cristiano Ronaldo for their early trip to Genoa, but move to 3-5-2 with Paulo Dybala, Mario Mandzukic and Alex Sandro.
It kicks off at Marassi at 11.30 GMT.
You can follow the build-up and action as it happens from all today’s Serie A games on the LIVEBLOG.
The Bianconeri are still buzzing after their Champions League comeback to beat Atletico Madrid 3-0 on the night, 3-2 on aggregate, setting up a quarter-final clash with Ajax.
Cristiano Ronaldo bagged a hat-trick midweek and Max Allegri has decided to rest the superstar, even if it means falling further behind Sampdoria’s Fabio Quagliarella in the Capocannoniere race.
Also left behind in Turin due to injury are Sami Khedira, Douglas Costa, Andrea Barzagli, Juan Cuadrado and Mattia De Sciglio.
Giorgio Chiellini and Blaise Matuidi are allowed a spot on the bench today, giving the likes of Daniele Rugani and Martin Caceres the chance to shine.
There’s a move to the 3-5-2 formation, with Mandzukic and Dybala upfront.
It’s a very special day for Mattia Perin, who returns to face his former club for the first time since the summer transfer to Turin.
Genoa have their goalkeeper Ionut Radu back in the side, after he missed last week’s defeat to Parma due to injury.
Andrea Favilli and Oscar Hiljemark are the only remaining absentees, as Coach Cesare Prandelli relies on strikers Antonio Sanabria and Christian Kouame.
Grifone centre-back Cristian Romero has practically agreed a move to Juventus, although it probably won’t be until June 2020.
Genoa have failed to keep a clean sheet against Juventus in their last nine competitive meetings, dating back to October 2014, conceding 19 goals.
If they pick up a result here, it’ll be the first time Genoa have managed to avoid defeat against Juventus over a Serie A season since 2011-12.
Genoa: Radu; Pereira, Romero, Zukanovic, Criscito; Lazovic, Radovanovic, Rolon, Lerager; Sanabria, Kouame
Juventus: Perin; Caceres, Bonucci, Rugani; Cancelo, Emre Can, Pjanic, Bentancur, Alex Sandro; Mandzukic, Dybala
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Football Italia staff